Can You Give Zosyn and Vanco Together?

badge holder, badge reel, bling badge, how to survive nursing school, ICU nurse, id badge holder, Labor and Delivery, lanyard, new grad RN, nurse, nursing school, post op nurse, registered nurse, retractable badge, RN, sizzle city, student nurse, tips for nurses -

Can You Give Zosyn and Vanco Together?

Pharmacist to New Grad Nurses

Tip of the Day

From Shelly Watson Pharm.D
I'm a Clinical Pharmacist mainly working in the ICU setting for the last 12 years.  I come across a lot of repeat questions and definitely from new grad nurses.  I love to teach so what better way than set up a blog where students and new grads can learn from.  
See if you know this one:
  • Question: Can you run Zosyn and Vancomycin together at the same time?
  • Answer: No

A lot of times, patients are on both Zosyn and Vancomycin empirically to treat PNA or Sepsis.   Since Zosyn and Vancomycin may be given every 8 to 12hrs depending on their kidney function, you will run into the dilemma of only having one line.  You may also be in a hospital where they incorporated long infusion Zosyn (over 4 hrs).  Therefore, it's important to know if you can give these two drugs together.  The answer is no.  

How would you approach this problem?  

  1. Start a new line
  2. If another line is impossible, have the pharmacist adjust the administration time of both medications.  I wouldn't adjust vancomycin administration  time without notifying a pharmacist since time of administration is crucial to proper trough levels. 

Hope this tip is helpful.  Follow our shop for more pharmacist to RN tips!

**Share with your fellow colleagues**  See if they can answer the question

Your tip of the day has been brought to you by....
-Shelly Watson Pharm.D